The diagnosis of EHF can be really very difficult as the early symptoms of this disease are very much similar to other diseases such as typhoid, malaria and cholera. Due to this many tests are to be conducted on a suspected victim to confirm the disease. These tests include blood film examination and stool sample test. Apart from these basic tests there are other tests such as ELISA, PCR and virus isolation.

If the patient shows majority of the symptoms of the disease and is suspected to be infected he/she should be tested for blood examination to detect the blood culture. If he/she has bloody vomit or diarrhea then the patient should be tested for the stool sample test. Different tests are used to find out the pathogen in different timeframes. Based on the severity the patient is subjected to any one of the tests. For example, polymerase chain reaction (PCR) antigen testing may be the fastest and most reliable tool available. PCR testing can identify a virus in 1 day. Isolating the virus may take 5 to 7 days to identify the pathogen.

The ELISA test (Antigen-capture Enzyme-Linked ImmunoSorbent Assay) is a serologic testing is done after few days from infection. PCR and virus isolation are done on victims of the disease. All the tests are to be conducted in high-containment labs with bio-safety level of 4. This bio-safety is necessary because animals are affected through airborne transmission and if diagnosis is not carried out within the containment chances of transmission are more. Thus bio-safety is recommended and monitored by the government organizations.

Electron Microscopy is used mainly to identify filoviruses in the tissues of infected or suspected victims. However results have been reassessed in places where outbreaks have occurred. Indirect Immunofluorescence test is the most common test done on EHF patients. The drawback faced by this is that it's not specific in nature. Thus consequently other advanced tests such as ELISA tests were designed.

The immunohistochemical test is done on the skin of the infected person after formalin has been applied. This is a very useful test in diagnosis and surveillance procedure. Apart from these other tests are Electron microscopy and Indirect Immunofluorescence test but these have certain limitations on the timeframe side. Since different tests take different time intervals, if an infected person is to take two or more tests for diagnosis of the disease, it may prove disadvantageous because only after the results of all tests arrive can the provider tell the result of diagnosis until which the patient has to be in confinement. If proper diagnosis is not carried out it may even prove menacing to the patient.

Based on the results of the conducted diagnostic tests, the disease can be controlled to a certain extent - but not with home medical supplies. Though the mortality rate is very high maybe future research can really bring more effective tests to bring down the mortality rate. No treatment developed so far has been proved to have put an end to the disease completely. They are only effective to an extent and the disease is still considered to be fatal.